Chemotaxis - Biological and Clinical Approaches
(Kőhidai L. Med. Habil., M.D., Ph.D.)
Schedule (Lectures in Hungarian)
1.
Chemotaxis – Significance in biology.
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2.
Evolution of signal molecules and their receptors.
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3.
Chemotaxis in invertebrate and vertebrate organisms.
(Extramural link suggested to view: A Day in the Life of a Social Amoeba)
4.
Bacterial chemotaxis - The well known signalling pathway.
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(Extramural link suggested to view:
Bacterial chemotaxis -KEGG Pathway Maps )
5.
Cytosceleton.
- Cell
adhesion.
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(Extramural link suggested to view: Video tour of cell motility
6.
Inflammation - The classic example
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(Extramural link suggested to view: Extravasation step-by-step
(Extramural link suggested to view: Life cycle of HIV; Life cycle of HIV+Drug,
More HIV: Life cycle; Fusion-Entry; Inhib.-Attachment; Inhib.-Co-receptor;
8.
Phagocytosis - Target reaction of chemotaxis.
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9. Proteomical characterization of chemotactic ligands
10. Immunological aspects of chemotaxis and the clinical significance.
11. Optimal chemotactic ligand – Exists or not ?
12.
Significance of chemotaxis in the development of symptoms and syndromes.
Significance in clinical interventions.
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13. Special
approaches of tumour biology and chemotaxis
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14. Life
without chemotaxis – Impossibile!
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15. Review of laboratory techniques applied for measurement of chemotaxis. – Practical demonstrations.
Course books (in Hungarian):
REGISTRATION to the course mailto:Kohlasz@dgci.sote.hu
Pages to download required softwares to see appendix materials: