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    Chemotaxis - Biological and Clinical Approaches

    (Kőhidai L. Med. Habil., M.D., Ph.D.)

 

Essay Topics

 

       Schedule (Lectures in Hungarian)

 1. Chemotaxis – Significance in biology.

 2. Evolution of signal molecules and their receptors.

 3. Chemotaxis in invertebrate and vertebrate organisms. 

     (Extramural link suggested to view: A Day in the Life of a Social Amoeba)

 4. Bacterial chemotaxis - The well known signalling pathway. 

     (Extramural link suggested to view:    

                                                    Bacterial chemotaxis

                                                    Bacterial chemotaxis -KEGG Pathway Maps )

 5. Cytosceleton.  - Cell adhesion.

     (Extramural link suggested to view:   Video tour of cell motility

                                                                Motor proteins)

 6. Inflammation - The classic example 

     (Extramural  link suggested to view: Extravasation step-by-step

                                                                Chemotaxis of neutrophils )

      7.  Chemokines

           (Extramural  link suggested to view: Life cycle of HIV; Life cycle of HIV+Drug

            More HIV: Life cycle; Fusion-Entry; Inhib.-Attachment; Inhib.-Co-receptor;

             Inhib.-Fusion)

 8. Phagocytosis - Target reaction of chemotaxis.

 9. Proteomical characterization of chemotactic ligands

 10. Immunological aspects of chemotaxis and the clinical significance.

 11. Optimal chemotactic ligand – Exists or not ?

 12. Significance of chemotaxis in the development of symptoms and syndromes.   Significance in clinical interventions.

 13. Special approaches of tumour biology and chemotaxis

 14. Life without chemotaxis – Impossibile!

 15. Review of laboratory techniques applied for measurement of chemotaxis. – Practical demonstrations.

 

Course books (in Hungarian):

pdf1

pdf2

 

REGISTRATION to the course mailto:Kohlasz@dgci.sote.hu

 

Pages to download required softwares to see appendix materials:

                                        QuickTime                             Microsoft Magyarország

 

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