Chemotaxis Group

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Recent publications:

Lajkó E, Szabó I, Andódy K, Pungor A, Mező G, Kőhidai L.Investigation on chemotactic drug targeting (chemotaxis and adhesion) inducer effect of GnRH-III derivatives in Tetrahymena and human leukemia cell line.J Pept Sci. 19, 46-58 /2013/

Kőhidai, L., Lajkó, E., Pállinger, É., Csaba, G. Verification of epigenetic inheritance in a unicellular model system. Multigenerational effects of hormonal imprinting. Cell Biol. Int. 36, 951–959 /2012/

Lang, J., Kohidai, L. Effects of the aquatic contaminant human pharmaceuticals and their mixtures on the proliferation and migratory responses of the bioindicator freshwater ciliate Tetrahymena. Chemosphere 89,592–601 /2012/

Kohidai, L. Tetrahymena pyriformis in motion. In: Microbiorobotics - Biologically Inspired Microscale Robotic Systems. Eds. Kim, MJ, Steager, E., Agung, AJ. Elsevier, pp 55-84 /2012/

Leurs, U., Lajkó, E.,Mező, G., Orbán, E., Öhlschläger, C.P., Marquardt, A., Kőhidai, L., Manea, M. GnRH-III based multifunctional drug delivery systems containing daunorubicin and methotrexate. Eur. J. Med. Chem. 52, 173-183 /2012/

Láng, O., Illyés, E., Menyhárd D.K., Láng, J., Sebestyén, F., Hudecz, F., Kőhidai, L. Chemotaxis induced by SXWS tetrapeptides in Tetrahymena—overlapping chemotactic effects of SXWS sequences and their identical amino acids. J. Mol. Recogn. 25, 24-31 /2012/

Lajkó, E. Polgár, L., Lengyel, J., Láng, O., Kőhidai, L., Magyar, K. Basic cell physiological activities (cell adhesion, chemotaxis, proliferation) induced by selegiline and its derivatives in Mono Mac 6 human monocytes. J. Neural Transm 119, 545-556 /2012/

Láng, J., Rákász, V., Magyar, A., Pállinger, É., Kőhidai, L. Chemotactic effect of odorants and tastants on the ciliate Tetrahymena pyriformis. J. Rec. Sign. Transd. 31, 423-433 /2011/

Sáfár, O., Kőhidai, L., Hegedűs, A. Time-delayed model of unibased movement of Tetrahymena pyriformis. Period. Math. Hung. 63, 215-225 /2011/

Díaz, E., Köhidai, L., Ríos, A., Vanegas, O., Ponte-Sucre, A. Chemotaxis assays in vitro in Leishmania sp. evaluation of the capillary-two chambers technique in promastigotes. Rev. Facult. Farm. 74, 31-39 /2011/

Book chapters:

Abdallah, M.W., Michel, T., Kohidai, L. Autism spectrum disorders and circulating chemokines. In: The Comprehensive Guide to Autism, Eds. Patel, VB, Preedy, VR., Martin, CR; Springer; doi: 10.1007/SpringerReference_331001

Kőhidai, L. MIGRATION OF IMMUNE COMPETENT CELLS, HOMING AND EXTRAVASATION IN INFLAMMATION. In: Seminars in Immunology. Ed. Fülöp, K.; Semmelweis University, Budapest; pp. 133-150 (2012) ISBN 978-963-9129-82-5

Kőhidai, L. DIE HOMING, DIE GEZIELTE MIGRATION VON IMMUNZELLEN. EXTRAVASATION IN ENTZÜNDUNGEN. Immunologie Seminare. Ed. Pap, E.; Semmelweis Universität, Budapest; pp. 148-162 (2012) ISBN 978-963-9129-83-2

Kőhidai, L. AZ IMMUNSEJTEK MIGRÁCIÓJA, HOMING ÉS GYULLADÁSOS EXTRAVAZÁCIÓ. In: Immunológiai szemináriumok. Ed. Fülöp, K.;Semmelweis Egyetem, Budapest; pp. 130-148 (2012) ISBN 978-963-9129-81-8

Recent oral presentations:

Kőhidai, L., Lajkó, E, Láng, J., Láng, O., Vizi, T., Csaba, G., Pállinger, É. Apoptotic and anti-apoptotic effects of prenatal drugs in BeWo human trophoblast cells. (xCELLigence System - Global User Conference 2012, Stockholm, 2012.)

    Láng, O., Láng, J., Mező, G., Hudecz, F., Kőhidai, L. Tetrahymena responses to vertebrate type cytokine receptor sequences - Structure- function relationships of (W)SXWS peptide library. (Ciliate Molecular Biology, FASEB SRC, Crete, 2011.)

    Kohidai, L., Szemes, A., Lajko, E., Lang, O. Chemotaxis induced by mono- and disaccharides in Tetrahymena pyriformis GL. (Ciliate Molecular Biology, FASEB SRC, Crete, 2011.)

    Kőhidai, L., Láng, O., Simonyi, D., Láng, J., Lajkó, E., Oláh, Cs., Pungor, A. Cell physiological effects elicited by silver nanoparticles - cytotoxicity, cell adhesion and migration monitored by impedanciometry in human THP-1 monocyte and HMEC-1 endothe cell lines. (1st Conference on Impedance-Based Cellular Assays, Regensburg, Germany, 2011.)

    Mező, G., Szabó, A., Lajkó, E., Szabó, I., Manea, M., Láng, O., Kőhidai, L. Peptide-drug bioconjugates containing different targeting moieties - The influence of the peptide carrier on the antitumor activity of drug containing bioconjugates. (4th European Conference on Chemistry for Life Sciences, Budapest, 2011.)

    Láng, J., Pomázi, K., Bősze. Sz., Mező, G., Hudecz, F., Kőhidai, L. Influence of physicochemical moieties of WSXWS-oligotuftsin conjugates on adhesion and chemotaxis - Effects of WSXWS-oligotuftsin conjugates on adhesion and chemotaxis on eukaryotic model cells. (4th European Conference on Chemistry for Life Sciences, Budapest, 2011.)

Recent poster presentations:

Lajkó, E., Polgár, L., Leurs, U., Manea, M., Szabó, I., Mező, G., Kőhidai, L. Significance of cell adhesion and chemotaxis in therapeutic targeting of tumor cell lines by cytotoxic GnRH-III conjugates. (xCELLigence System - Global User Conference 2012, Stockholm, 2012.)

Polgár, L., Soós, P., Lajkó, E., Láng, O., Merkely, B., Kőhidai, L. Impedimetry – Novel method for measurement of platelet adhesion. (xCELLigence System - Global User Conference 2012, Stockholm, 2012.)

    Kőhidai, L., Láng, O., Simonyi, D., Láng, J., Lajkó, E., Oláh, Cs., Pungor, A. Cell physiological effects elicited by silver nanoparticles - cytotoxicity, cell adhesion and migration monitored by impedanciometry in human THP-1 monocyte and HMEC-1 endothe cell lines. ( S7 - 1st Conference on Impedance-Based Cellular Assays, Regensburg, Germany, 2011.)

    Dávid, G., Láng, O., Légrády, D., Kőhidai, L. Time dependency of the electrical noise of melanoma cell lines. (1st Conference on Impedance-Based Cellular Assays, Regensburg, Germany, 2011.)

    Láng, O., Tóth, K., Lajkó, E., Wegener, J., Kőhidai, L. Effect of light on cell adhesion and motility. 1st Conference on Impedance-Based Cellular Assays, Regensburg, Germany, 2011.)

    Láng, J., Tóthfalusi, L., Kőhidai, L. Single and mixture toxicity of pharmaceuticals present in the aquatic environment to the ciliate Tetrahymena pyriformis. (3rd International Conference on Occurrence, Fate, Effects, and Analysis of Emerging Contaminants in the Environment, Koppenhága, Denmark, 2011.)

    Lajkó, E., Polgár, L., Lengyel, J., Magyar, K., Kőhidai, L. Molecular structure dependent cell physiological activities of R-deprenyl and its derivatives - Characterization of the cell physiological activities (chemotaxtis, adhesion, proliferation) induced by R-deprenyl and its derivatives. (4th European Conference on Chemistry for Life Sciences, Budapest, 2011.)

    Slezák, S., Lajkó, E., Pállinger, É., Bai- K.B., Dombi, C., Lohinai, Z.M., Mező, G., Gera, I., Kőhidai, L. Applications of chemotactic drug targeting in prevention of periodontitis. (45th CED-IADR, Budapest, 2011.)

    Láng, O., Bai, K.B., Sáfár, O., Varga, G. Mező, G., Kőhidai, L. Analysis of cell adhesion/motility in parotid gland cell lines. (45th CED-IADR, Budapest, 2011.)

    Polgár, L., Soós, P., Lajkó, E., Láng, O., Merkely, B., Kőhidai, L. Measurement of platelet adhesion – Application of a new, impedance based technique. (19th International Meeting of the Alpe Adria Association of Cardiology, Budapest, 2011.)

    Polgar, L., Soos, P., Lajko, E., Lang, O., Olah, Cs., Pungor, A., Merkely, B., Kohidai, L. Impedanciometry – Introducing a novel technique for the measurement of platelet adhesion. (Euthrombosis 2011, Porto, Potrugal, 2011.)